Plex is the centerpiece of my media center software. It provides access to pretty much all of my media in a nice, polished interface. That said, Asset UPnP is my primary mechanism for accessing music.

I use MakeMKV for ripping disc contents into digital format, then Handbrake for converting the ripped contents into a compatible format.

I use PhotoDirector for organizing my photos and DVD Profiler for managing my DVD collection.

My digital music is in iTunes but I keep track of the combined digital and disc music collection using Music Collector.

My backup solution is iDrive, which handles off-site backup. That, combined with the File History backup in Windows 10 (which also gets backed up by iDrive), has me covered.